If you’ve ever been showing a presentation or a video, you know how embarrassing it can be when system sounds such as alerts, errors, and notifications interrupt your audio, especially when you’re projecting to a PA system or loudspeakers.
In OS X, there’s a couple of cool little options that you can apply to your audio settings so that, if you are say, listening to your music while you clean, or showing a movie on your big TV, then you won’t be interrupted by Frog, Funk, Bottle, or any of the other system alerts.
Full article here:
How to Adjust Volume Settings for Individual Audio Devices and Sound Effects in OS X (How-To Geek)